Be able to consent to participate in the study
	Be 18 years of age or more
	Have laboratory evidence of HIV infection
	Have a CD4+ cell count less than or equal to 300 cells/mm3 or CD4 percent less than or equal to 15%, and a viral load above 5,000 copies/ml
	Have taken anti-HIV medicines at least for the last three months
	Not be pregnant or breast-feeding
	Have experienced the failure of at least two different multi-drug regimens that included drugs of all three classes
	Not have a serious, uncontrolled opportunistic infection (OI) within 14 days of screening
	Not be currently taking any of the following medications: amiodarone, astemizole, terfenadine, cisapride, ergot derivatives, lovastatin, simvastatin, pimozide, propafenone, midazolam, triazolam, bepridil, clozapine, bupropion, rifampin, St. John's Wort or phenobarbital.

Please check with your doctor or one of our study contacts if you have any questions regarding these requirements.