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Standard Care - up to four anti-HIV drugs

There is a belief that if minor changes are made to the drugs you take, the decline in the CD4 count and rise in viral load may be slowed. The changes to drug therapy would be made with the results of a resistance test to guide choice.

While no dramatic changes are expected for participants in this group, there may be benefits as the regimen should be more stable and easier to follow than treatment groups 2 and 4. There is some evidence that this approach may still have some benefit.

Some of the other treatment groups have high amounts of risk associated with them along with increases in the number of drugs to take.


Pros
Not much change.
Fewer drugs to take (than some other treatment groups).
Less risk of opportunistic infections if no HIV- drug-free period.
Cons
Less chance of a dramatic positive change.
Using up to four drugs may not be as potent as using six anti-HIV drugs.
May continue to develop resistance to existing drugs.