FRANÇAIS  |  CONTACT US
0
0


0 0 0 0



Mega ART - Five or more anti-HIV drugs

The resistance test that will be done when a person is screened for this study is likely to show resistance to many drugs. Where little or no resistance is shown to a drug, it will be chosen (unless the person has been unable to tolerate it before and does not want to give it another try).

The thinking behind this treatment group is that even if the virus is slightly resistant, each drug is still doing something against HIV. So if you get several small bits of work from several drugs you may get more effect and less virus. A doctor may suggest more than five drugs; some have tried up to 11 with favourable results in the reduction in HIV viral load.


Pros
A fall in viral load has been seen in some smaller studies.
Less risk of opportunistic infections with constant anti-HIV drugs.
This approach is successful in other areas such as cancer treatment.
Cons
More drugs can theoretically increase risk of side effects.
Difficulty taking large combinations at different times.
It is unknown how long the effect will last.